Biomarkers for Cognitive Aging Part I

Biomarkers of Cognitive Training Effects in Aging

An increasing number of studies have relied on brain imaging to assess the effects of cognitive training in healthy aging populations and in persons with early Alzheimer's disease or mild cognitive impairment (MCI). At the structural level, cognitive training in healthy aging individuals has been associated with increased brain volume, cortical thickness, and density and coherence of white matt...

Environmental Effects on Mechanical Properties of Glass/Epoxy and Fiber Metal Laminates, Part I: Hygrothermal Aging

In this article, the effect of hygrothermal aging on mechanical properties of fiber metal laminates (FMLs) and E-glass/epoxy (GE) composites is investigated. First, FML and GE specimens were built using wet lay-up technique under vacuum pressure. Hygrothermal aging simulation was then carried out on both specimen types in distilled water at a constant temperature of 90 °C for 5 weeks. The resul...

[Immune dysfunction and cognitive deficit in stress and physiological aging (Part I): Pathogenesis and risk factors].

The concept of stressful cognitive dysfunction, which is under consideration in this review, allows picking out several therapeutic targets. The brain, immune and endocrine systems being the principal adaptive systems in the body permanently share information both in the form of neural impulses and soluble mediators. The CNS differs from other organs due to several peculiarities that affect loc...

Are processing speed tasks biomarkers of cognitive aging?

We examined the association between 5 processing speed measures and general cognitive ability in a large (>900) sample of relatively healthy men and women at age 70. The processing speed tests were the Wechsler Digit Symbol-Coding and Symbol Search, simple reaction time, 4-choice reaction time, and inspection time. To inquire whether the processing speed tasks might be biomarkers of cognitive a...

Part I Defences of the aging gastrointestinal tract